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ABSTRACT To relieve the threat to human health and welfare imposed by an expanding number of major health challenges, biomedical research and its implementation in clinical practice must be supported and accelerated. To achieve this in the next dec- ade, a paradigm shift toward personalised medicine will be of major importance, with the overriding aim of improving every citizen’s lifelong health and well-being. Basic, trans- lational, and clinical research of high quality provides the foundation for European health systems, offering the opportunity to link with social, cultural, and environmen- tal expertise to facilitate world-class multidisciplinary research. The global revolution in biomedicine is also providing access to new technologies that will re- quire expansion and implementation to tackle the health challenges that Europe faces. A European platform engaging all key stakeholders to ensure discovery and delivery of these technologies will be crucial. Establishment of a European Strategic Action for Healthier Citizens is also recommended, to assist in strategic long-term healthcare research, planning, including preventive measures, and delivery of best practice across Europe. In most European countries, healthcare is a driving factor for investment – in industry, in educa- tion and training, and in the European knowledge base for wealth creation. The proposals in this document will enhance investment and create jobs in research and innovation, im- prove healthcare status of Europe- ans and at the same time drive down integrated societal costs of healthcare. 21


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