DTU National Veterinary Institute
European Ossabaw Facility. Obesity prone minipigs for
What do we offer?
The Ossabaw minipig is probably the best available model
of diet-induced Metabolic Syndrome and its sequelae, and
constitutes a highly relevant non-rodent humantranslational
model for the complex condition of the
A breeding herd of Ossabaw minipigs will be in established
at DTU Risø (near Roskilde, 30 km from Copenhagen), in
the 1st quarter of 2018.
Interested parties from academia and industry are invited
to explore and make use of this pig model.
Ossabaw minipigs are currently bred only at a single site in
the world (Purdue/Indiana University, USA), however now
the Technical University of Denmark (DTU) makes Ossabaw
pigs available for European researchers from the first non-
US Ossabaw breeding herd. This creates new possibilities
for both academia and the pharmaceutical industry in
Europe, which will gain access to the translational model of
choice for pre-clinical research on complex diseases and
syndromes related to obese conditions.
What differentiates us?
The obese Ossabaw pig has repeatedly been pointed out as showing the broadest compliance with Metabolic
Syndrome features. Already after 9 weeks of feeding with a high-calorie, atherogenic diet, female Ossabaw pigs
nearly double their percentage body fat, show insulin resistance, impaired glucose tolerance, dyslipidemia (profound
increase in the ratio of low-density to high-density lipoprotein cholesterol as well as hypertriglyceridemia),
hypertension, and early coronary atherosclerosis - all of which are parts of Metabolic Syndrome
What do we look for at the Medico Bazar?
Collaboration on research in the Ossabaw minipig model on Obesity related conditions such as cardiovascular
disease, non-alcoholic steatohepatitis, diabetes etc., including partners for joint grant project proposals as well as
fee for service partners.
Customers needing to use an advanced minipig model for biomedical research.
Thomas Kledal, PhD & MBA
Peter Heegaard, Professor, MSc,